Cis versus trans DNA cleavage in Flp-half-site dimers. The labeled
![Cis versus trans DNA cleavage in Flp-half-site dimers. The labeled](https://www.researchgate.net/publication/13362663/figure/fig3/AS:281949789802499@1444233476791/Cis-versus-trans-DNA-cleavage-in-Flp-half-site-dimers-The-labeled-right-half-site-alone.png)
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The development of genome editing tools as powerful techniques with versatile applications in biotechnology and medicine: CRISPR/Cas9, ZnF and TALE nucleases, RNA interference, and Cre/loxP
![](https://www.sdbonline.org/sites/fly/pathway/presynapse.jpg)
Neuromuscular Junction
![](https://ars.els-cdn.com/content/image/1-s2.0-S0021925818900906-gr1.jpg)
Functional Roles of Individual Recombinase Monomers in Strand Breakage and Strand Union during Site-specific DNA Recombination - ScienceDirect
![](https://image.slidesharecdn.com/sitespecificrecombinationandmultiplexcrispr-240204172101-ec733fec/85/site-specific-recombination-and-multiplex-crisprpptx-3-320.jpg?cb=1707067634)
Site specific recombination and Multiplex CRISPR.pptx
![](https://static.cambridge.org/binary/version/id/urn:cambridge.org:id:binary-alt:20181001224655-73197-mediumThumb-17037fig2_3.jpg?pub-status=live)
Biology of Endonucleases (Zinc-Finger Nuclease, TALENs and CRISPRs) and Regulatory Networks (Part I) - Genome Editing and Engineering
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CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules - Chemical Science (RSC Publishing) DOI:10.1039/D0SC06973F
Reactions of Cre with Methylphosphonate DNA: Similarities and Contrasts with Flp and Vaccinia Topoisomerase
![](https://www.researchgate.net/publication/13362663/figure/fig2/AS:281949789802498@1444233476731/Trans-mode-of-DNA-cleavage-A-The-three-potential-modes-of-trans-DNA-cleavage-are.png)
Trans mode of DNA cleavage. ( A ) The three potential modes of trans
![](https://www.cell.com/cms/attachment/e431a6b9-2505-490a-9c5d-fb6281f2f77e/gr3.jpg)
Mu Transpositional Recombination: Donor DNA Cleavage and Strand Transfer in trans by the Mu Transposase: Cell
![](https://pubs.acs.org/cms/10.1021/acs.chemrev.1c00260/asset/images/medium/cr1c00260_0001.gif)
Directed Evolution: Methodologies and Applications
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Separation Moieties And Methods Of Use Thereof WINSTON; William ; et al. [Werewolf Therapeutics, Inc.]
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DNA recombination and RNA cleavage activities of the Flp protein: roles of two histidine residues in the orientation and activation of the nucleophile for strand cleavage - ScienceDirect
![](https://i1.rgstatic.net/ii/profile.image/279592511262729-1443671457865_Q64/Shwetal-Mehta.jpg)
PDF) Wild-type Flp recombinase cleaves DNA in trans
![](https://www.embopress.org/cms/asset/dc7303bd-0cd1-4439-a920-323532a71e64/embj7591513-fig-0001-m.jpg)
Wild‐type Flp recombinase cleaves DNA in trans