Comparison of three methods for gene isoform identification. Lines
![Comparison of three methods for gene isoform identification. Lines](https://www.researchgate.net/publication/299646229/figure/fig3/AS:391412534267948@1470331428978/High-sequence-identity-of-10-msg-isoforms-of-P-jirovecii-previously-identified-by-Sanger_Q320.jpg)
Download scientific diagram | Comparison of three methods for gene isoform identification. Lines with different colors represent different sequences from publication: Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads | Background Gene isoforms are commonly found in both prokaryotes and eukaryotes. Since each isoform may perform a specific function in response to changing environmental conditions, studying the dynamics of gene isoforms is important in understanding biological processes and | PacBio, Bioinformatics Analysis and Nucleic Acid Repetitive Sequences | ResearchGate, the professional network for scientists.
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Schema of the clustering-based data analysis procedure using PacBio
![](https://www.researchgate.net/profile/Sergio-Pimpinelli/publication/13606228/figure/fig2/AS:11431281176084501@1690013359004/The-cytoplasmic-oligomers-of-HP1-and-differentially-salt-extracted-nuclear-fractions_Q320.jpg)
Da Wei (David) HUANG, Big Data Scientist in Bioinformatics, National Institutes of Health, MD, NIH, Bioinformatics and Molecular Analysis Section (BIMAS)
![](https://www.researchgate.net/publication/299646229/figure/fig2/AS:391412534267947@1470331428853/Schema-of-the-clustering-based-data-analysis-procedure-using-PacBio-long-reads-The_Q320.jpg)
Comparison of three methods for gene isoform identification. Lines with
![](https://www.researchgate.net/publication/362157882/figure/fig1/AS:1182487355101184@1658938363012/Search-for-studies_Q320.jpg)
William LAU, Doctor of Philosophy, National Institutes of Health, MD, NIH
![](https://www.researchgate.net/publication/366883934/figure/fig3/AS:11431281153834716@1682564263802/Contributors-to-increased-day-1-IFNg-responses-in-male-participants-who-had-recovered_Q320.jpg)
William LAU, Doctor of Philosophy, National Institutes of Health, MD, NIH
![](https://www.researchgate.net/publication/359057913/figure/fig1/AS:11431281212214425@1702558633198/HSV-2-genome-and-alignments-of-seven-contigs-A-The-alignments-of-the-seven-contigs_Q320.jpg)
Brad SHERMAN, Bioinformatics Manager, Master of Science, Leidos Biomedical Research, Inc., Frederick, Laboratory of Human Retrovirology and Immunoinformatics
![](https://www.researchgate.net/profile/Richard-Lempicki/publication/312081612/figure/tbl1/AS:669146907942922@1536548463512/figure-tbl1_Q320.jpg)
Richard LEMPICKI, Senior Scientist, Ph.D, Leidos Biomedical Research, Inc., Frederick, Laboratory of Immunopathogenesis and Bioinformatics
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Brad SHERMAN, Bioinformatics Manager, Master of Science, Leidos Biomedical Research, Inc., Frederick, Laboratory of Human Retrovirology and Immunoinformatics
![](https://www.researchgate.net/publication/299646229/figure/fig3/AS:391412534267948@1470331428978/High-sequence-identity-of-10-msg-isoforms-of-P-jirovecii-previously-identified-by-Sanger_Q320.jpg)
Comparison of three methods for gene isoform identification. Lines with
![](https://i1.rgstatic.net/ii/profile.image/272362029449236-1441947577022_Q64/Art-Shaffer.jpg)
Da Wei (David) HUANG, Big Data Scientist in Bioinformatics, National Institutes of Health, MD, NIH, Bioinformatics and Molecular Analysis Section (BIMAS)
![](https://www.researchgate.net/publication/299646229/figure/fig1/AS:391412534267946@1470331428825/Comparison-of-three-methods-for-gene-isoform-identification-Lines-with-different-colors.png)
Comparison of three methods for gene isoform identification. Lines with
![](https://i1.rgstatic.net/ii/profile.image/1116175807332357-1643128458690_Q64/Liang-Ma.jpg)
PDF) Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads
![](https://i1.rgstatic.net/ii/profile.image/272212724809772-1441911979707_Q64/Brad-Sherman.jpg)
Brad SHERMAN, Bioinformatics Manager, Master of Science, Leidos Biomedical Research, Inc., Frederick, Laboratory of Human Retrovirology and Immunoinformatics
![](https://www.researchgate.net/publication/298346202/figure/fig1/AS:339924705398788@1458055773384/sual-summary-of-1-367-differentially-expressed-genes-following-cryopreservation-The_Q320.jpg)
Richard LEMPICKI, Senior Scientist, Ph.D, Leidos Biomedical Research, Inc., Frederick, Laboratory of Immunopathogenesis and Bioinformatics