High body temperature increases resistance to
Viral infections affect the elderly more frequently than the younger population. Moreover, elderly individuals also have lower mean body temperatures. Taking cues from these clinical observations, a team of researchers from The University of Tokyo undertook a study to find the missing link between body temperature and infection resistance. Findings indicate that increased body temperature suppresses virus replication and excessive inflammatory responses.
![](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-023-39569-0/MediaObjects/41467_2023_39569_Fig1_HTML.png)
High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection
![](https://www.ims.u-tokyo.ac.jp/ichinohe-lab/top1.jpg)
東京大学医科学研究所 一戸研究室
![](https://www.cidrap.umn.edu/sites/default/files/styles/layout_large/public/images/news/thermometer_in_the_sun.jpg?itok=mH_-nOKS)
Study finds antibiotic resistance rise tied to hotter temps
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41467-023-39569-0/MediaObjects/41467_2023_39569_Fig5_HTML.png)
High body temperature increases gut microbiota-dependent host resistance to influenza A virus and SARS-CoV-2 infection
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses
![](https://www.ims.u-tokyo.ac.jp/imsut/content/000006788.png)
THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO
![](https://www.ims.u-tokyo.ac.jp/ichinohe-lab/4fdf61e07592597dcd3831b29f76adac-768x512.jpg)
東京大学医科学研究所 一戸研究室
![](https://www.ims.u-tokyo.ac.jp/imsut/content/000003895.jpg)
Press Releases|THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defenses
![](https://www.ims.u-tokyo.ac.jp/imsut/content/000006965.png)
THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO
![](https://www.ims.u-tokyo.ac.jp/imsut/content/000000544.png)
THE INSTITUTE OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKYO